{"id":11124,"date":"2024-07-29T09:44:16","date_gmt":"2024-07-29T09:44:16","guid":{"rendered":"https:\/\/cyber-valley.de\/news\/cyber-physische-zwillinge-menschlicher-organe\/"},"modified":"2026-07-15T14:44:48","modified_gmt":"2026-07-15T14:44:48","slug":"cyber-physische-zwillinge-menschlicher-organe","status":"publish","type":"news","link":"https:\/\/cyber-valley.de\/de\/news\/cyber-physische-zwillinge-menschlicher-organe\/","title":{"rendered":"Cyber-physische Zwillinge menschlicher Organe"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong><p>&nbsp;<\/p>\n\n<p>Dieser Artikel ist nur auf Englisch verf&uuml;gbar.<\/p>\n\n<p><meta charset=\"UTF-8\" \/>A research project funded by the Cyber\u00a0Valley Research Fund has developed cutting-edge cyber-physical twins of human organs. This breakthrough was facilitated by unrestricted resources and support for scientific research through the contributions of six Cyber\u00a0Valley founding partners: Amazon, BMW, Bosch, IAV,&nbsp;Porsche, and ZF. &nbsp;<\/p><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><meta charset=\"utf-8\"\/><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Dr. Tian Qiu led the project in collaboration with three medical departments at the University Hospitals in T\u00fcbingen and Freiburg. The project team\u00a0successfully created and studied\u00a0six highly realistic organ models, including the kidney, bladder, prostate, liver, vagina, and brain. These models combine the advantages of physical and cyber models to improve the collection\u00a0of hard-to-get biomedical data under realistic conditions for analysis and modeling.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For the physical models, the project team optimized 3D printing and soft material molding techniques to replicate the anatomy and texture of human organs. Additionally, they engineered new hydrogel materials that behave like real soft tissue in surgical procedures. The team also created a brain model comprising composite hydrogel that exhibits life-like mechanical properties and high optical transparency, enabling high-resolution imaging.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The project\u2019s cyber models incorporated sensing technologies such as optical imaging, ultrasound imaging, and electrical sensing. These integrated systems can generate large amounts of data, making possible real-time feedback and quantitative evaluation of surgical outcomes. The project also leveraged Augmented Reality (AR) to enhance medical training. Medics participated in initial trials by applying the new cyber-physical organ models to optimize surgical instruments and digital surgical training.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Cyber\u00a0Valley Research Fund has allocated five million euros to promote innovation and scientific excellence. Research groups were encouraged to submit project proposals that\u00a0were\u00a0evaluated according to ethical and societal considerations. \u00a0<br\/><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>This project yielded the following peer-reviewed publications:\u00a0<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\"><li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"1\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{225}\" paraid=\"1258116517\">Choi et al. (2021): Soft urinary bladder phantom for endoscopic training, Ann. Biomed. Eng., 49, 2412-2420, DOI: <a rel=\"noopener\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s10439-021-02793-0\" target=\"_blank\">10.1007\/s10439-021-02793-0\u00a0<\/a><\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Hackner et al. (2021): Panoramic imaging assessment of different bladder phantoms \u2013 an evaluation study, Urology, 156, e103-e110, DOI: <a rel=\"noopener\" href=\"https:\/\/doi.org\/10.1016\/j.urology.2021.05.036\" target=\"_blank\">10.1016\/j.urology.2021.05.036<\/a><\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Kim et al. (2022): A high-fidelity artificial urological system for the quantitative assessment of endoscopic skills, J. Funct. Biomater., 13(4)301, DOI: <a rel=\"noopener\" href=\"https:\/\/www.mdpi.com\/2079-4983\/13\/4\/301\" target=\"_blank\">10.3390\/jfb13040301\u00a0<\/a><\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Tan et al. (2021): Soft liver phantom with a hollow biliary system, Ann. Biomed. Eng., 49, 2139-2149, DOI: <a rel=\"noopener\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s10439-021-02726-x\" target=\"_blank\">10.1007\/s10439-021-02726-x\u00a0<\/a><\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Tonyali S., Mueller A.-S. et al. (2024): Automated and quantitative surgical technique\u00a0evaluation for TURP. In preparation<\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Mueller A.-S., et al. (2024): Surgical training of bladder tumor resection on hydrogel models with quantitative assessment based on 3D ultrasound scanning. In preparation<\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Li et al. (2020): Realistic full urinary tract phantom for endoscopic training, The European Association of Endoscopic Surgery (EAES), Poster\u00a0<\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Kim et al. (2021): Organ Phantom for the Assessment of Robotic Surgeries, Hamlyn\u00a0Symposium on Medical Robotics (HSMR), Poster\u00a0<\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Kim et al. (2021): Computer-assisted quantitative assessment of endo. skills based on a urological phantom, 55th DGBMT Ann. Conf. on Biomed. Eng., Talk, 66, S212-217, <a rel=\"noopener\" href=\"https:\/\/www.semanticscholar.org\/paper\/Computer-Assisted-Quantitative-Assessment-of-Skills-Yeon-Kim\/7c5017beea726b5a08363eaaf34cba94107e505a?utm_source=direct_link\" target=\"_blank\">Link to abstract<\/a><\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Kim et al. (2022): A hybrid surgical simulator for interactive endoscopic training, IEEE Inter. Conf. of the Engineering in Medicine and Biology Society (EMBC), Poster, DOI:\u00a0<a rel=\"noopener\" href=\"https:\/\/ieeexplore.ieee.org\/document\/9871697\" target=\"_blank\">10.1109\/EMBC48229.2022.9871697<\/a>\u00a0<\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Tan et al. (2021): A realistic liver phantom for the training and quantitative evaluation of endoscopic skills, 17th World Congress of Endo. Surgery (WCES), Poster, 344272, P201\u00a0<\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Mueller A.-S., et al. (2023): Surgical training of tumor resection on hydrogel models with quantitative assessment based on 3D ultrasound scanning. DKFK German Cancer\u00a0Research Congress (GCRC). Poster\u00a0<\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Fischer, F.; et al. (2023): Wireless force sensing of a micro-robot penetrating a viscoelastic solid, International Nonlinear Dynamics Conference (NODYCON), Talk\u00a0<\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Replica LL\" data-leveltext=\"%1.\" data-list-defn-props='{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"2\" role=\"listitem\">\n<p paraeid=\"{fef39828-6e71-4fd8-b831-5426ff390fa4}{243}\" paraid=\"2117759708\">Fischer, F. et al. (2022): 3D fabrication of microvascular networks on artificial organ models for endoscopic surgical simulation. Poster. Future 3D Additive Manufacturing \u2013 The 3DMM2O Conference<\/p>\n<\/li><\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Public events and public media reports:\u00a0<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\"><li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"1\" data-font=\"Aptos\" data-leveltext=\"-\" data-list-defn-props='{\"335552541\":1,\"335559683\":0,\"335559684\":-2,\"335559685\":720,\"335559991\":360,\"469769226\":\"Aptos\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"-\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"3\" role=\"listitem\">\n<p lang=\"EN-US\" paraeid=\"{1a228cb1-db50-4e78-9a7a-6e7537f0bb90}{179}\" paraid=\"1336186384\" xml_lang=\"EN-US\">Presentation of German Chancellor Dr. Merkel during virtual visit of Cyber\u00a0Valley, 2020; <a rel=\"noopener\" href=\"https:\/\/www.student.uni-stuttgart.de\/en\/news\/all\/Chancellor-Angela-Merkel-and-Minister-President-Winfried-Kretschmann-visit-Cyber-Valley\/\u00a0\" target=\"_blank\">Link to article<\/a><\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"2\" data-font=\"Aptos\" data-leveltext=\"-\" data-list-defn-props='{\"335552541\":1,\"335559683\":0,\"335559684\":-2,\"335559685\":720,\"335559991\":360,\"469769226\":\"Aptos\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"-\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"3\" role=\"listitem\">\n<p lang=\"EN-US\" paraeid=\"{26975793-d7f4-4842-baee-15bc8ef8a4f1}{234}\" paraid=\"484376980\" xml_lang=\"EN-US\">University of Stuttgart representing at Hannover Messe 2023; <a rel=\"noopener\" href=\"https:\/\/www.f05.uni-stuttgart.de\/en\/faculty\/news\/news\/Visionary-exhibits-at-the-Hannover-Messe-Hanover-Trade-Fair-2023\/\u00a0\" target=\"_blank\">Link to article <\/a><\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"3\" data-font=\"Aptos\" data-leveltext=\"-\" data-list-defn-props='{\"335552541\":1,\"335559683\":0,\"335559684\":-2,\"335559685\":720,\"335559991\":360,\"469769226\":\"Aptos\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"-\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"3\" role=\"listitem\">\n<p lang=\"EN-US\" paraeid=\"{1a320b39-e068-46ca-965d-67ed7989b7ba}{56}\" paraid=\"1497891801\" xml_lang=\"EN-US\">Stuttgarter Zeitung; <a rel=\"noopener\" href=\"http:\/\/https:\/\/www.stuttgarter-zeitung.de\/inhalt.hightech-medizin-aus-stuttgart-wie-miniroboter-durch-den-koerper-reisen.a529868f-60e6-4060-8076-4e7303e9771d.html\u00a0\" target=\"_blank\">Link to article<\/a><\/p>\n<\/li>\n<li aria-setsize=\"-1\" data-aria-level=\"1\" data-aria-posinset=\"4\" data-font=\"Aptos\" data-leveltext=\"-\" data-list-defn-props='{\"335552541\":1,\"335559683\":0,\"335559684\":-2,\"335559685\":720,\"335559991\":360,\"469769226\":\"Aptos\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"-\",\"469777815\":\"hybridMultilevel\"}' data-listid=\"3\" role=\"listitem\">\n<p lang=\"EN-US\" paraeid=\"{bcda9e51-1501-48d6-ac94-1544173db6fd}{170}\" paraid=\"1258113885\" xml_lang=\"EN-US\">Spotify, Cyber\u00a0Valley Podcast, AI in Medicine;\u00a0<a rel=\"noopener\" href=\"http:\/\/https:\/\/open.spotify.com\/episode\/2k61gAXaTtSDkEJPYeb2fn\u00a0\" target=\"_blank\">Link to spotify episode<\/a><\/p>\n<\/li><\/ol>\n","protected":false},"featured_media":11761,"parent":0,"template":"","meta":{"_acf_changed":false},"cv-tag":[],"location":[],"network-role":[],"news-category":[374],"user-group":[245],"class_list":["post-11124","news","type-news","status-publish","has-post-thumbnail","hentry","news-category-health-network","user-group-researcher"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cyber-physische Zwillinge menschlicher Organe - Cyber Valley<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cyber-valley.de\/de\/news\/cyber-physische-zwillinge-menschlicher-organe\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cyber-physische Zwillinge menschlicher Organe - Cyber Valley\" \/>\n<meta property=\"og:description\" content=\"&nbsp; Dieser Artikel ist nur auf Englisch verf&uuml;gbar. A research project funded by the Cyber\u00a0Valley Research Fund has developed cutting-edge cyber-physical twins of human organs. This breakthrough was facilitated by unrestricted resources and support for scientific research through the contributions of six Cyber\u00a0Valley founding partners: Amazon, BMW, Bosch, IAV,&nbsp;Porsche, and ZF. &nbsp; Dr. Tian Qiu [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cyber-valley.de\/de\/news\/cyber-physische-zwillinge-menschlicher-organe\/\" \/>\n<meta property=\"og:site_name\" content=\"Cyber Valley\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-15T14:44:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cyber-valley.de\/wp-content\/uploads\/2026\/02\/CV_Research_Fund.png\" \/>\n\t<meta property=\"og:image:width\" content=\"2048\" \/>\n\t<meta property=\"og:image:height\" content=\"1152\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data1\" content=\"3\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cyber-valley.de\\\/de\\\/news\\\/cyber-physische-zwillinge-menschlicher-organe\\\/\",\"url\":\"https:\\\/\\\/cyber-valley.de\\\/de\\\/news\\\/cyber-physische-zwillinge-menschlicher-organe\\\/\",\"name\":\"Cyber-physische Zwillinge menschlicher Organe - 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