Methods for mining the adaptive immune repertoire for SARS-CoV-2 diagnostics and therapeutics

ellis 15 April 2020 - 15 April 2020

15 April 2020 • 13:55 - 14:10

(University of Oslo)

The adaptive immune system, which is responsible for detection and clearance of pathogens (e.g., virus infections), records each past and ongoing battle with disease into so-called immunological memory. Thus, the adaptive immunity is both natural sensor of disease as well as a therapeutic. The immune memory is recorded by “immune receptors” - short genetic sequences specific for each disease. I will provide an overview of the ongoing efforts in academia and industry to develop artificial intelligence methods that exploit our immune system’s capacity to assist in diagnosis (immunodiagnostics) as well as develop next- generation biotherapeutics (monoclonal antibodies, T-cell therapies).